Single-center Experience With Vascular Reconstruction for Soft Tissue Sarcoma Resection

Resection of soft tissue sarcoma the extremities may require vascular reconstructive surgery due to direct involvement or proximity tumor major structures. Autogenous conduit is preferred for reconstruction, but not always available. The purpose this study evaluate long term survivorship and outcomes in resection with explore utility prosthetic requiring reconstruction. This was a retrospective single-center review patients 18 years older undergoing without between 1990 2019. Data obtained from institutional Clinical Research Warehouse manual chart review. All had diagnosis sarcoma. Group I (30 patients) were involvement, II (15 included that did III required Excluded those other than resected at an outside hospital. primary outcome graft patency. Secondary overall survival, freedom amputation, amputation rate, wound healing, infection distal site recurrence. Sixty included. For autologous used two 13 patients. Prosthetic patency 92%, 77%, 50%, 45%, 27% 30 days, 6 months, 1 year, 2 years, respectively. Groups I, II, rates 0%, 7%, 20%, respectively (P = .033). 5-year survival 88%, 58%, .02) (Table). There no difference groups healing viable alternative autogenous reconstruction during resection. Sarcoma has higher lower as compared reconstruction.TableFive-year outcomesSTS VRS (n 30)STS 15)STS 15)P valueAmputation rate0 (0)1 (6.67)3 (20).033Patient 1-year29 (97)13 (87)13 (87).36Patient 5-years22 (88)7 (0.58)5 (45).02Freedom days1636.73 (±1047.36)1674.5 (717-2214.5)1202 (±1315.96)711.5 (282.5-1609.5)803.87 (±904.66)472 (166-1176).16STS last follow-up, (717-2214.5)1222.5 (±1297.9)711.5 (293-1609.5)967.47 (±971.47)610 (295-1240).14Wound duration, days56 (16-52.5)47 (25-57)32 (19.5-118).95Infection rate within days6 (20)4 (26.67)3 (20).91Recurrence after STS 5 years5 (16.67)5 (33.33)7 (15).096Distal time diagnosis2 (6.67)2 (13.33)0 (0).36Distal resection3 (10)1 (13.33)1.0Distal years6 (20)8 (53.33)4 (26.66).067STS, Soft sarcoma; VRS, surgery.Data are presented number (%), median (IQR), mean (±standard deviation). Open table new tab